Add ground beef to a medium skillet along with Worcestershire sauce, salt, pepper, onion powder, and garlic powder. Cook over medium-high heat until well browned.
Prepare the Big Mac Sauce by whisking all of the ingredients together.
Assemble the salad by combining the lettuce, beef, cheese, pickles, and onions. Then top with sesame seeds, croutons, and sauce.
Notes
Leave the croutons out if you want a low carb, Keto-friendly salad.