Preheat oven to 375 degrees.
In a small dish, soak the cubed bread with milk, ensuring it is completely saturated. Let soak for 10 minutes.
While bread is soaking gently crumble ground beef into a large bowl
In a separate bowl add eggs, Worcestershire, brown sugar, salt, pepper, paprika, garlic powder, onion powder, and cayenne pepper. Mix to combine and ensure eggs are beaten.
Add soaked bread to the bowl with seasonings and work together to incorporate and break down bread so there are no large chunks.
Add the seasonings bowl to the crumbled beef and gently work it together with your fingers to ensure seasonings are evenly dispersed among the meat.
Scoop out 2 tablespoons of meat at a time and gently roll together between your hands to form into a ball and set on a jelly roll pan. Repeat with all remaining meat.*
Paint meatballs with BBQ sauce and place in the oven for 20 minutes, or until internal temperature reaches 160 degrees.
Remove from oven and serve with additional BBQ sauce on the side.